Identifying virulence factors in an opportunistic pathogenic bacterium
The client wanted to confirm and identify virulence factors in a gut bacterium that normally resides harmlessly in animals but can cause infection under stress or immunosuppression. Population structure complicated the distinction between pathogenic and commensal...
Unlocking immunogenicity insights from clinical reports with NLP
Most information about the immunogenicity of therapeutic peptides is locked in unstructured clinical reports. The client wanted to extract and structure this data to inform development of safe and effective treatments. Our Approach We built a robust extraction...
De-risking & automating antibody discovery through rationalisation of in-vitro maturation
After selecting a binder, the client wanted to improve its potency by rationalising invitro maturation. Manual screening of mutations is labour-intensive and error-prone. Our Approach We applied AbQuery and Antibody-extractor to rationalise in-vitro maturation and...