Discovering biomarkers in cerebrospinal fluid EVs

Discovering biomarkers in cerebrospinal fluid EVs

The institute wanted to identify diagnostic biomarkers for neurodegenerative diseases by analysing proteins in extracellular vesicles from cerebrospinal fluid. Shotgun proteomics data contained missing values and required rigorous processing. Our Approach We applied...
Custom pipeline for metagenomics & metabolomics data

Custom pipeline for metagenomics & metabolomics data

The Challenge The client needed a complete software suite for automated analysis and visualisation of metagenomic and metabolomic data. Existing workflows involved multiple tools and manual data transfers, limiting efficiency. Our Approach We standardised and...
Characterising inflammation using spatial transcriptomics

Characterising inflammation using spatial transcriptomics

The Challenge The client wanted to use spatial single‑cell transcriptomics to study the molecular histopathology of chronic inflammatory bowel disease. No benchmarked workflows existed, and the technology required sophisticated analysis. Our Approach We re‑annotated...
Inferring causality of the microbiome in gastric ulceration

Inferring causality of the microbiome in gastric ulceration

The Challenge The faculty sought to understand how feed size and gastric microbiota contribute to ulcer development in pigs. Identifying causal relationships required advanced biostatistics and careful handling of complex microbiome data. Our Approach We built causal...
Custom single‑cell analytic pipeline & visualization toolkit

Custom single‑cell analytic pipeline & visualization toolkit

The Challenge The client works with large single‑cell RNA‑sequencing datasets that require advanced processing, scalable infrastructure and intuitive exploration tools. They wanted a central system for processing, analysing and visualising these data. Our Approach We...