Gene expression biomarkers in osteoarthritis
The Challenge The client developed a cartilage‑on‑a‑chip technology and a gene panel to monitor treatment effects. They needed additional in vivo human evidence and comprehensive literature review to refine the panel and convince investors. Our Approach We...
In silico modeling supports fast‑tracking of market entry
The Challenge To obtain regulatory approval and accelerate market entry, Paleo needed to demonstrate that their animal‑free myoglobins are safe and to optimise production yields. Assessing immunogenicity and toxicity and modelling production processes required...
Discovering biomarkers in cerebrospinal fluid EVs
The institute wanted to identify diagnostic biomarkers for neurodegenerative diseases by analysing proteins in extracellular vesicles from cerebrospinal fluid. Shotgun proteomics data contained missing values and required rigorous processing. Our Approach We applied...