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Development journey
Services
Bio|Verse®
Case studies
About
Careers
News
Blogs
Let’s discuss how we can turn your data into real scientific impact.
Contact us >
Comprehensive literature analysis
BioLizard used BioReflect to help PamGene analyze literature on genes linked to a rare eye disease. An NLP-driven platform provided a complete, interactive overview, revealing key publications, one-third of which would have been missed with a manual search.
About the client
PamGene is dedicated to supporting physicians and scientists in finding solutions and answers to improve and optimise patient treatment and understand diseases. Their multiplex, functional kinase activity profiling technology reveals the bigger picture of cellular signalling and provides mechanistic insights needed to fully understand diseases and cell alterations.
Project overview
One of PamGene’s research projects was focused on a set of genes implicated in a rare eye disease, and their potential as drug targets.
One of the goals of this project was to get an updated literature overview of this rare ocular disease and related genes in order to identify potential associations and mechanistic insights. They did not want to miss any relevant publications with a manual search, which is why they were interested in using BioReflect to generate a comprehensive overview of the relevant literature.
“Without BioReflect, we would have missed several relevant publications in our literature search.” – PamGene
Our approach
Develop an algorithm that queries literature databases, finds the relevant publications and retrieves the abstracts and relevant metadata.
Build an NLP model to discover the topics of the downloaded publications.
Develop an interactive, browser-based application for visualization and exploration of the results.
Bundle and compress the results and front-end application in a single folder for the user to download, so that users can explore the results offline and on their own infrastructure.
Results
Ability to see and explore complete literature search results in a single overview.
NLP-driven topic analysis helps find the most relevant publications faster.
A third of the papers used in the review would have been missed without BioReflect.
For more information, try the BioReflect demo today!
Oncology drug development often begins in patients, allowing early safety and efficacy insights. Yet many cancer drugs still fail in the clinic. We validate the target but ignore its context within the tumor microenvironment. This article explores why spatial biology may improve clinical success.
BioLizard has been named “Bioinformatics Innovation of the Year” in the 2025 BioTech Breakthrough Awards. The honor spotlights Bio|Verse® Navigator, a visual analytics workspace that unifies complex R&D data so scientists can decide faster, with confidence.
Bioinformatics pipelines break for the smallest reasons: package updates, shifting dependencies, or “it only works on my machine.” This post explains why experienced software engineers and DevOps practices (Git, CI/CD, IaC) are essential to keep workflows reproducible, stable, and scalable.